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January 1, 1967Journal of Clinical PathologyOpen Access

Measurement of platelet adhesiveness including the use of diatomaceous silica (celite)

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Key result

Methods for measuring platelet adhesiveness to glass and celite were developed and their reproducibility was assessed in healthy donors compared to an ADP method.

Population

Healthy donors

Comparison

Measurement of platelet adhesiveness to glass… vs Measurement of platelet adhesiveness using…

Design

Other

Authors

GPG. D. PegrumCharing Cross HospitalSSSidney ShawDalhousie UniversitySWS. WolffCharing Cross Hospital

Discussion

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Implication

New adhesiveness assays need patient validation before use; leaves open standardization for thrombotic risk assessment.

Structured PICO

P
Population
A series of healthy donors assessed for platelet adhesiveness using different methodological techniques.
E
Exposure
Measurement of platelet adhesiveness to glass and celite
C
Comparator
Measurement of platelet adhesiveness using adenosine diphosphate (ADP)
O
Outcome
Reproducibility of the resultssurrogate

The study assesses the reproducibility of different methods for measuring platelet adhesiveness using glass, celite, and ADP.

Cite This Study

Pegrum et al. (1967) studied Healthy. Measurement of platelet adhesiveness to glass and celite vs. Adenosine diphosphate (ADP) method was evaluated on Reproducibility of platelet adhesiveness methods. Methods for measuring platelet adhesiveness to glass and celite were developed and their reproducibility was assessed in healthy donors compared to an ADP method.

synapsesocial.com/papers/6a9fa3f4c2a6bb3d9844a5dahttps://doi.org/10.1136/jcp.20.1.65
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Rapid adhesive platelet count in whole blood1964 · 31 citations
  2. 2HUMAN BLOOD COAGULATION AND ITS DISORDERS1963 · 360 citations
  3. 3The adhesiveness of native platelets and its prevention1961 · 158 citations