August 1, 1985Critical Care Medicine
Complications after overdose with tricyclic antidepressants
Why the study?
Does the absence of initial ECG abnormalities and need for intubation predict a benign clinical course in patients with tricyclic antidepressant overdose?
Population
72 consecutive cases of tricyclic antidepressant overdose admitted from the emergency ward to the ICU…
Design
Cohort
Follow-up
mean ICU stay of 2.1 days, plus post-ICU transfer
Authors
Discussion
Loading...
Member takes
Implication
May indicate low-risk TCA overdose without ICU need; hypothesis-generating and requires prospective validation.
Structured PICO
Does the absence of initial ECG abnormalities and need for intubation predict a benign clinical course in patients with tricyclic antidepressant overdose?
P
Population
72 consecutive cases of tricyclic antidepressant (TCA) overdose admitted from the emergency ward to the ICU between 1977 and 1982.
O
Outcome
Development of new ECG abnormalities, need for ventilatory support, or late complicationshard clinical
TCA overdose patients without initial ECG abnormalities or need for ventilatory support may not require ICU admission simply for intensive observation.
Cite This Study
Stern et al. (1985) studied this question.