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A combination of atomic force microscopy, quartz crystal microbalance and fluorescence spectroscopy shed light on the mechanism of interaction of hIAPP with zwitterionic model membranes, and allowed us to speculate the toxic behaviour of hIAPP in diabetes mellitus type II. The results suggest that damage of zwitterionic lipid bilayers and fibrillogenesis are two different phenomena.
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Scalisi et al. (2010) studied this question.
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