Carcinoid tumours arise from specialized epithelial cells in the gastro-intestinal tract known as Kultschitzky cells, which in recent years have been shown to secrete 5-hydroxytryptamine.The presence of excessive quantities of this substance in the blood of patients with metastasizing carcinoid tumours may produce a characteristic clinical syndrome of cutaneous flushing,
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Ralph C. Williams (1960) studied this question.
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