Answers are grounded in this paper and cite their sources.
A new and practical method has been developed for the synthesis of 2,4-disubstituted quinolines via one-pot three-component reaction of o-amino arylketones, aldehydes and ammonium acetate in high yields by using DDQ in CH3CN under mild conditions. Neutral conditions, atom economy, easy work-up procedures and compatible with different functional groups are the salient features of this protocol.
No takes yet. Share an insight, caveat, or question.
Bose et al. (2020) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: