Key result
Aneurysms lateral to the curve of the parent artery had significantly higher wall shear stress than those inside or outside the curve, highlighting the importance of parent artery geometry.
Why the study?
Does the configuration of a saccular aneurysm relative to the parent artery affect intra-aneurysmal hemodynamics?
Does the configuration of a saccular aneurysm relative to the parent artery affect intra-aneurysmal hemodynamics?
The configuration of a saccular aneurysm relative to the parent artery significantly affects intra-aneurysmal hemodynamics, specifically wall shear stress.
Aneurysm location relative to parent artery curvature may modulate wall shear stress; hypothesis-generating for human rupture risk models.
We show the importance of arterial geometry in intra-aneurysmal hemodynamics. Using a new geometric parameterized saccular aneurysm model including parameters for parent artery shape and the configuration of the aneurysm in the parent artery, we performed a parametric computational fluid dynamics study. We examined lateral saccular aneurysm models with different aneurysm shapes (i.e., the ratio of aneurysm height to aneurysm neck diameter) and different configurations (i.e., the torsion angle of the aneurysm to the upstream part of the parent artery). The aneurysm lateral to the curve of the parent artery had significantly higher wall shear stress than the aneurysm inside or outside the curve of the artery, even with the same shape of the aneurysm. Our findings suggest the important role played by the configuration of the aneurysm relative to the parent artery in intra-aneurysmal hemodynamics.
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Sato et al. (2007) studied Saccular aneurysm. Aneurysm configuration relative to parent artery vs. Different aneurysm shapes and configurations was evaluated on Wall shear stress. Aneurysms lateral to the curve of the parent artery had significantly higher wall shear stress than those inside or outside the curve, highlighting the importance of parent artery geometry.
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