Key result
The median probability of infection given a single inhaled TCID50 of foot and mouth disease virus was estimated to be 0.031 for cattle and 0.045 for sheep.
Why the study?
What is the dose-response relationship for inhaled foot and mouth disease virus in cattle and sheep?
Population
Cattle and sheep exposed to foot and mouth disease virus
Design
Preclinical
Authors
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Supports FMD risk modeling in livestock; leaves open validation for natural exposure scenarios.
What is the dose-response relationship for inhaled foot and mouth disease virus in cattle and sheep?
Effect estimate: 0.031 (cattle) (95% CI 0.018-0.052)
The study provides dose-response curves and uncertainty distributions for foot and mouth disease infection in cattle and sheep for use in quantitative risk assessments.
French et al. (2002) studied Foot and mouth disease (n=57). Inhaled foot and mouth disease virus was evaluated on Probability of infection given a single inhaled TCID50 (0.031 (cattle), 95% CI 0.018-0.052). The median probability of infection given a single inhaled TCID50 of foot and mouth disease virus was estimated to be 0.031 for cattle and 0.045 for sheep.
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