I131-Labeled Fat and Pancreatin as a Differential Absorption Test in Patients With Steatorrhea

Article1 June 1960I131-LABELED FAT AND PANCREATIN AS A DIFFERENTIAL ABSORPTION TEST IN PATIENTS WITH STEATORRHEAABRAHAM A. POLACHEK, M.D., ROBERT F. WILLIARD, B.S.ABRAHAM A. POLACHEK, M.D.Search for more papers by this author, ROBERT F. WILLIARD, B.S.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-52-6-1195 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt has been shown1, 2 that patients with steatorrhea, whether due to pancreatic insufficiency or malabsorption syndrome, have low blood I131 levels after a fat meal with radioiodinated triolein. The two conditions may be differentiated by giving an additional meal of the labeled hydrolysis product of fat, radioiodinated oleic acid.3-6 Normal blood levels of I131 are obtained in the group with pancreatic disease, contrasted with low levels in patients with intestinal malabsorption.Substitution therapy with pancreatic extract for exocrine pancreatic insufficiency has been used for a long time. A preparation of desiccated hog pancreas with high lipolytic activity7has been...Bibliography1. ShingletonBaylinIsleySandersRuffin WWGJJKAPJM: The evaluation of pancreatic function by use of I131-labeled fat, Gastroenterology 32: 28, 1957. CrossrefMedlineGoogle Scholar2. RuffinKeeverChearsShingletonBaylinIsleySanders JMJCCWWGJJKAP: Further observations in the use of I131-labeled lipids in the study of diseases of the gastrointestinal tract, Gastroenterology 34: 484, 1958. CrossrefMedlineGoogle Scholar3. 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Digest. Dis. 3: 682, 1958. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Fort Howard, Maryland*Received for publication August 18, 1959.From the Radioisotope and Medical Services, Veterans Administration Hospital, Fort Howard, Maryland.†Present address: Veterans Administration Hospital, Memphis, Tennessee.‡Viokase, produced by Viobin Corporation, Monticello, Illinois.Requests for reprints should be addressed to Abraham A. Polachek, M.D., Chief, Radioisotope Service, Veterans Administration Hospital, 3900 Loch Raven Boulevard, Baltimore 18, Maryland (Fort Howard Division). PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDifferential diagnosis of maldigestion and malabsorption of fatThe radioisotope laboratory in clinical gastroenterologyThe I131-triolein absorption testPancreatic replacement therapy in the treatment of pancreatic steatorrhoeaZur Prüfung der131J-Trioleintoleranz bei Krankheiten der VerdauungsorganeDIVERTICULOSIS OF THE JEJUNUM WITH MACROCYTIC ANEMIA AND STEATORRHEA*ABRAHAM A. POLACHEK, M.D., WALTER J. PIJANOWSKI, M.D., JOSEPH M. MILLER, M.D. 1 June 1960Volume 52, Issue 6Page: 1195-1200KeywordsBloodBlood plasmaFatsMedical servicesPancreasPancreatic diseasesPancreatitisPatients ePublished: 1 December 2008 Issue Published: 1 June 1960 PDF downloadLoading ...