What question did this study set out to answer?

To evaluate the clinical relationship between periodontitis and postmenopausal osteoporosis across published observational studies.

October 20, 2023HeliyonOpen Access

Association between periodontal disease and osteoporosis in postmenopausal women: A systematic review and meta-analysis

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Authors

JQJing QiGansu Provincial Hospital JCJiahui ChenHunan University of Science and Technology YPYunqing PangMinzu University of China

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Implication

Meta-analysis reveals increased periodontitis severity in postmenopausal women with osteoporosis, suggesting systemic bone loss accelerates oral tissue degradation.

Key Points

To evaluate the clinical relationship between periodontitis and postmenopausal osteoporosis across published observational studies.
Systematic review and meta-analysis of 28 observational studies comprising 19,611 postmenopausal participants (5,813 with osteoporosis and 13,798 controls) identified across seven major databases up to July 1, 2023.
Methodological quality was assessed using the Cochrane Risk of Bias tool for clinical trials and the Newcastle-Ottawa Scale for cohort and case-control studies.
Pooled mean differences (MD) and 95% confidence intervals (CI) for continuous clinical outcomes were synthesized using RevMan 5.4.
Osteoporotic women exhibited significantly higher clinical attachment loss (MD = 0.89 mm, 95% CI [0.48, 1.30], p < 0.00001) and deeper probing depths (MD = 0.27 mm, 95% CI [0.13, 0.41], p = 0.0001) compared to non-osteoporotic controls.
Gingival recession (MD = 0.28 mm, 95% CI [0.20, 0.35], p < 0.00001), simplified oral hygiene index (MD = 1.32, 95% CI [1.12, 1.51], p < 0.00001), and bleeding on probing (MD = 12.71%, 95% CI [3.24, 22.18], p = 0.009) were also significantly elevated in women with osteoporosis.
Bone mineral density was significantly lower in the osteoporosis group (MD = -0.41 U/cm², 95% CI [-0.77, -0.05], p = 0.03), whereas alveolar crestal height loss showed no significant difference between groups (MD = -1.76%, 95% CI [-3.64, 0.12], p = 0.07).

Cite This Study

Qi et al. (2023) studied this question.

synapsesocial.com/papers/6a9fb190ea7eeb5cbeec6fe7 https://doi.org/10.1016/j.heliyon.2023.e20922

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Implication

Meta-analysis reveals increased periodontitis severity in postmenopausal women with osteoporosis, suggesting systemic bone loss accelerates oral tissue degradation.

Association between periodontal disease and osteoporosis in postmenopausal women: A systematic review and meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Association between periodontal disease and osteoporosis in postmenopausal women: A systematic review and meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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