Key result
A 29-year-old woman completely recovered from a major overdose of 900-970 mg of Lioresal (baclofen) following 72 hours of intensive cardiovascular and respiratory supportive care.
Case Report (n=1)
Major baclofen overdose can present with deep coma and absent brain stem reflexes, but complete recovery is achievable with intensive supportive care.
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Intensive supportive care may enable recovery after massive baclofen overdose; single case report leaves open generalizability and optimal protocols.
George W. Paulson (1976) conducted a case report in Lioresal overdose (n=1). Lioresal (baclofen) was evaluated on Clinical recovery. A 29-year-old woman completely recovered from a major overdose of 900-970 mg of Lioresal (baclofen) following 72 hours of intensive cardiovascular and respiratory supportive care.