Aspects on the Glucose Metabolism of the Hypothalamus and the Pituitary in Goats

Andersson B., S. Larsson F. Pocchiari. Aspects on the glucose metabolism of the hypothalamus and the pituitary in goats. With the aid of 14C‐labelled glucose certain aspects of glucose metabolism have been studied in different parts of the hypothalamus and in the posterior and anterior pituitary. The metabolic pattern of the hypothalamus differs from that of the pituitary. Also within the hypothalamus certain differences exist with regard to the fate of the glucose in the incubation medium. Large amounts of GABA are found in the hypothalamus and the posterior pituitary. Glutamine was formed in all samples studied. In the anterior pituitary, glutamine contributes to about 25 % of all amino acids formed from the radioactive glucose. In the hypothalamus and the posterior pituitary about 10 μg per 25 mg of tissue per hour of the glucose present in the incubation medium was converted into amino acids. The findings are discussed in relation to previous biochemical and physiological studies on this subject.