Key result
A novel balloon-expandable stent demonstrated increased tapering and decreased foreshortening with higher expansion pressure and ring amplitude gradients in a finite element method simulation.
Finite element modeling demonstrates that increasing the gradient of ring amplitude in a novel balloon-expandable stent improves tapering and reduces foreshortening for use in tapered vessels.
Supports tapered-vessel stent optimization; hypothesis-generating and requires human validation before any clinical consideration.
In-stent restenosis still remains an obsession to cardiologist, especially in tapered vessels. In this paper, we designed a novel balloon-expandable stent for tapered vessel and proposed a finite element method (FEM) to study the expansion of the novel stent. The effect of stent design parameters on stent tapering and foreshortening were also researched. Results show that the radial displacement of stent proximal end was always larger than that of stent distal end during stent expansion, and the stent had a tapered shape as a whole after expansion. The degree of stent tapering observed increased with the expansion pressure increase. Besides, increasing the gradient of ring amplitude not only could increase the tapering degree of stent after expansion, but also could decrease stent foreshortening, improving the positioning accuracy after stent implantation. In conclusion, FEM can quantify expansion performance of novel balloon-expandable stents and help designers to devise and assess new stent designs for tapered vessel.
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Shen et al. (2015) studied In-stent restenosis in tapered vessels. Novel balloon-expandable stent for tapered vessel was evaluated on Stent tapering and foreshortening during expansion. A novel balloon-expandable stent demonstrated increased tapering and decreased foreshortening with higher expansion pressure and ring amplitude gradients in a finite element method simulation.
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