Key result
A two-stent strategy for PCI of bifurcation lesions and the use of drug-eluting stents do not increase the risk of stent thrombosis compared to provisional stenting and bare metal stents.
Why the study?
Does the use of a two-stent strategy or DES increase the risk of stent thrombosis in PCI of bifurcation lesions compared to provisional stenting or BMS?
Does the use of a two-stent strategy or DES increase the risk of stent thrombosis in PCI of bifurcation lesions compared to provisional stenting or BMS?
In PCI for bifurcation lesions, the risk of stent thrombosis remains low with two-stent strategies and DES, emphasizing the importance of appropriate DAPT, meticulous technique, and IVUS guidance.
Supports low thrombosis risk with two-stent DES strategies in bifurcations; leaves open need for randomized confirmation.
Percutaneous coronary intervention of bifurcation lesions is known to be associated with higher risk of complications than non-bifurcation lesions. In the drug-eluting stent (DES) era, the risk of stent thrombosis (ST) is of particular concern because of its catastrophic consequences and late occurrence. The risk of ST in PCI of bifurcation lesions remains low even with the use of a two-stent strategy compared with a provisional side branch stenting strategy. Also, the use of DES has no higher risk of ST compared with bare metal stents. Prevention of ST in PCI of bifurcation lesions remains pivotal and must include appropriate duration of dual antiplatelet therapy, meticulous attention to stent deployment techniques, and use of intravascular ultrasound for guidance whenever needed.
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HUAY‐CHEEM TAN (2009) conducted a review in Bifurcation lesions undergoing percutaneous coronary intervention. Two-stent strategy and drug-eluting stents vs. Provisional side branch stenting and bare metal stents was evaluated on Stent thrombosis. A two-stent strategy for PCI of bifurcation lesions and the use of drug-eluting stents do not increase the risk of stent thrombosis compared to provisional stenting and bare metal stents.
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