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Continuous refinement of technique and the logical structuring of procedural steps have driven the evolution of peroral endoscopic myotomy (POEM), facilitating its widespread adoption and enhancing procedural effectiveness. POEM offers key advantages, including precise esophageal myotomy and rapid postoperative recovery. Its clinical indications have expanded beyond classic achalasia to encompass a broader spectrum of nonachalasia esophageal motility disorders.1 According to the American Gastroenterological Association expert review,1 POEM is currently indicated for achalasia types I, II, and III as well as for nonachalasia spastic disorders such as esophagogastric junction outflow obstruction, diffuse esophageal spasm, and hypercontractile esophagus.
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Yasutoshi Shiratori (2025) studied this question.
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