A unified classification of cancers: An oncotaxonomy with symbols

Despite greater uniformity in nomenclature due to the acceptance of a TNM (tumor, node, metastases) system of classification, a divergence of criteria exists concerning classification. In the majority of schemata, at specific organ sites, the UICC and AJCCS do not agree in many of the T and N categories creating confusion due to the adoption of a similar language. By linguistic analysis, a symbolic code was developed to provide a basis for a unified classification of cancer. A single set of criteria are defined in a cancer paradigm that is applicable to all cancers independent of the site of origin. The need to provide a consistent and clear language requires a standardization of the definition work-up to determine the true extent of tumor. The unified classification, if used generally, would allow for a better means of reaching true multidisciplinary decision-making in cancer management.