The genuine sapogenin 20 (S) -protopanaxatriol (1) and its corresponding prosapogenin 20 (S) -ginsenoside-Rh1 (3) were prepared by direct treatment of the peracetate of 20 (S) -ginsenoside-Rg2 in an alcoholic alkaline solution. Two kinds of alkaline conditions were compared.
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Chen et al. (1987) studied this question.