Key result
Wide variations in mesenteric perfusion pressure produced no alterations in systemic pressure, indicating that mesenteric pressure receptors do not significantly contribute to reflex blood pressure regulation.
Why the study?
Do mesenteric pressure receptors contribute to the reflex regulation of systemic blood pressure in animal models?
Population
14 animals undergoing isolated abdominal aorta perfusion or isolated superior mesenteric arterial system…
Comparison
Mesenteric artery occlusion and variations in… vs Carotid artery occlusion; baseline responses…
Design
Preclinical
Authors
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No role for mesenteric pressure receptors in reflex BP control in this model; leaves open relevance to human physiology and clinical translation.
Do mesenteric pressure receptors contribute to the reflex regulation of systemic blood pressure in animal models?
Mesenteric pressure receptors do not appear to contribute significantly to the reflex regulation of systemic blood pressure, with observed pressure changes likely resulting from mechanical blood diversion.
BOYER et al. (1960) studied Systemic blood pressure regulation (n=14). Mesenteric artery occlusion and perfusion pressure variations vs. Carotid artery occlusion was evaluated on Systemic blood pressure response. Wide variations in mesenteric perfusion pressure produced no alterations in systemic pressure, indicating that mesenteric pressure receptors do not significantly contribute to reflex blood pressure regulation.
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