What is the clinical evidence from this study?

Study design: Case Report. Population: Disease of the left coronary artery (n=1). Intervention: Ventricular fibrillation. Primary outcome: Sudden death.

What question did this study set out to answer?

To document and analyze the terminal cardiac mechanisms responsible for sudden, unexpected death in individuals with coronary artery disease.

June 7, 1941JAMA

Ventricular Fibrillation Causing Sudden Death of a Patient With Disease of the Left Coronary Artery

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Key result

Ventricular fibrillation was identified as the terminal cardiac mechanism causing sudden death in a patient with disease of the left coronary artery.

Key Points

To document and analyze the terminal cardiac mechanisms responsible for sudden, unexpected death in individuals with coronary artery disease.
Reviewed documented literature of electrocardiograms recorded at the exact moment of sudden cardiac death.
Evaluated clinical and electrocardiographic records of terminal events in coronary disease, referencing historical literature compiled through 1939.
Literature review identified only four previously published electrocardiographic recordings demonstrating ventricular fibrillation during sudden cardiac death.
Terminal mechanisms in coronary occlusion and angina pectoris involve either chaotic ventricular fibrillation or ventricular standstill triggered by vagal overstimulation.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

A single patient with disease of the left coronary artery who experienced sudden death.

Outcome

Terminal cardiac mechanism (ventricular fibrillation causing sudden death)hard clinical

Provides rare direct electrocardiographic evidence of ventricular fibrillation as the terminal mechanism of sudden death in coronary artery disease.

Discussion

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Implication

Documents VF as terminal rhythm in one CAD sudden death; hypothesis-generating and should not change practice.

Cite This Study

Ivan J. Thompson (1941) conducted a case report in Disease of the left coronary artery (n=1). Ventricular fibrillation was evaluated on Sudden death. Ventricular fibrillation was identified as the terminal cardiac mechanism causing sudden death in a patient with disease of the left coronary artery.

synapsesocial.com/papers/6a9fc105603ff62333618726 https://doi.org/10.1001/jama.1941.62820230001009

View Full Paper

Ask AI

Bookmark

Ventricular Fibrillation Causing Sudden Death of a Patient With Disease of the Left Coronary Artery

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Ventricular Fibrillation Causing Sudden Death of a Patient With Disease of the Left Coronary Artery

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider