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May 1, 1986Journal of Clinical MicrobiologyOpen Access

Sensitivity of different assay systems for immunoglobulin M responses to varicella-zoster virus in reactivated infections (zoster)

Nathalie J. Schmidt Ann M. Arvin

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Abstract

An immunoglobulin M response to varicella-zoster virus was detected in 70% of zoster patients by solid-phase radioimmunoassay, in 52% by indirect immunofluorescence, in 48% by neutralization on sucrose density gradient fractions, and in 27% by an antibody class capture enzyme immunoassay. The patients showed marked variations in their varicella-zoster virus immunoglobulin M responses detectable in the different assays.

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Schmidt et al. (1986) studied this question.

synapsesocial.com/papers/6a9fc1a6b709eacd8e71df22 https://doi.org/10.1128/jcm.23.5.978-979.1986

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