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September 1, 1972CirculationOpen Access

Left Heart Function in Children with Tetralogy of Fallot before and after Palliative or Corrective Surgery

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Why the study?

Does palliative or corrective surgery improve left heart function in children with tetralogy of Fallot?

Population

58 children with tetralogy of Fallot evaluated preoperatively, 31 after shunt procedure, and 24 after…

Comparison

Palliative shunt procedure or complete… vs Preoperative baseline values and normal…

Design

Cohort

Authors

JJJay M. JarmakaniUCLA Medical CenterTGT.P. GrahamUC San Diego Health SystemRCRamon V. CanentWomen & Children's Hospital of Buffalo

Discussion

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Implication

LV function remains depressed after TOF repair; leaves open whether earlier intervention or adjunctive therapies can restore LVEF.

Structured PICO

Does palliative or corrective surgery improve left heart function in children with tetralogy of Fallot?

P
Population
58 children with tetralogy of Fallot (TF) evaluated preoperatively, 31 after shunt procedure, and 24 after complete correction.
I
Intervention
Palliative shunt procedure or complete corrective surgery
C
Comparator
Preoperative baseline values and normal reference values
O
Outcome
Left heart volume and left ventricular mass (LV mass) calculated from biplane cineangiocardiogramssurrogate

Left ventricular function is depressed in patients with tetralogy of Fallot and remains depressed despite palliative or corrective surgery.

Cite This Study

Jarmakani et al. (1972) studied this question.

synapsesocial.com/papers/6a9fc5c47b6409934544ab31https://doi.org/10.1161/01.cir.46.3.478
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Physiologic Studies Early after Repair of Tetralogy of Fallot1963 · 33 citations
  2. 2Characterization of Left Heart Volumes and Mass in Normal Children and in Ifants with Intrinsic Myocardial Disease1968 · 59 citations
  3. 3Ventricular Pressure-Flow Dynamics in Tetralogy of Fallot1966 · 37 citations
  4. 4Left Heart Volume Estimation in Infancy and Childhood1971 · 206 citations
  5. 5Variations of Left Ventricular End-Diastolic Pressure, Volume, and Ejection Fraction with Changes in Outflow Resistance in Anesthetized Intact Dogs1968 · 50 citations