Summary The biological compatibility of an ethylene imine derivative (Scutan) and a self‐curing methyl methacrylate resin (Sevriton) was assessed in in vitro (cell culture) and in vivo (monkey teeth) tests. In vitro, both materials were toxic when freshly prepared, but Scutan less than Sevriton. Set specimens of both materials were non‐toxic in the experiments with 4 h cell‐material contact. In the 24 h experiments, however, Sevriton had a toxic effect. In vivo experiments confirmed that Sevriton may cause reactions in the pulp which makes it unsuitable for use in direct contact with vital dentine. The pulp reaction caused by Scutan, however, was of a mild nature. It was concluded, therefore, that Scutan may safely be used to make temporary crowns and bridges according to a direct technique.
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Dahl et al. (1974) studied this question.
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