CO/Alkene Copolymers as a Promising Class of Biocompatible Materials, 2. Bone Growth Directed Performance of Bone Marrow Cell Spreading

The influence of polymer polarity of three different CO/alkene copolymers on the production of bone materials by human bone marrow cells was demonstrated. The effects were measured by a specific immunohistochemical glycoprotein (osteonectin, osteopontin) test. Von Kossa staining, as an integral indicator for the formation of hard tissue on the biomaterial surfaces, visualized the obtained findings. The results clearly demonstrated an increase in mineralization activities with decreasing polarity of the tested polymers. Von Kossa staining of octadecene‐propene‐carbonmonoxide matrix (OdPCO). magnified image Von Kossa staining of octadecene‐propene‐carbonmonoxide matrix (OdPCO).