Is there a prognostic relevance of electrophysiological studies in bundle branch block patients?
Key result
The length of the HV interval during electrophysiological study was not associated with the later development of third-degree AV block or increased mortality.
Why the study?
Does the HV interval measured during an EP study predict the development of permanent AV block or mortality in patients with symptomatic bifascicular block and first-degree AV block?
Population
30 consecutive patients with symptomatic bifascicular block and first-degree AV block, mean age 74.8 ± 8.6…
Comparison
Electrophysiological study to measure HV… vs Comparison across different HV interval lengths.
Design
Cohort
Follow-up
53 ± 31 months
Authors
Discussion
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Implication
HV interval length adds no value for predicting AV block or mortality; leaves open identification of reliable conduction disease markers.
Study Design
Type
Cohort (n=30)
Structured PICO
Does the HV interval measured during an EP study predict the development of permanent AV block or mortality in patients with symptomatic bifascicular block and first-degree AV block?
P
Population
30 patients (mean age 74.8 years, 16.7% female) with symptomatic bifascicular block and first-degree AV block followed for a mean of 53 months.
E
Exposure
Electrophysiological (EP) study to measure HV interval before device implantation.
C
Comparator
Comparison across different HV interval lengths (<70 ms, >70 to ≤100 ms, >100 ms).
O
Outcome
Development of permanent complete (third-degree) atrioventricular block and mortality.hard clinical
The length of the HV interval during an EP study does not predict the development of third-degree AV block or mortality in patients with symptomatic bifascicular block and first-degree AV block, challenging current guideline recommendations for pacemaker implantation based solely on this metric.
Cite This Study
Bogossian et al. (2017) conducted a cohort in symptomatic bifascicular block and first-degree AV block (n=30). Prolonged HV interval vs. Shorter HV interval was evaluated on development of third-degree AV block or increased mortality. The length of the HV interval during electrophysiological study was not associated with the later development of third-degree AV block or increased mortality.