Key result
In an 18-year-old male with Long QT syndrome type 8, mexiletine infusion reduced the QTc(B) interval from 451 msec to 376 msec.
Why the study?
Does mexiletine or propranolol improve QTc interval in a patient with non-Timothy syndrome LQT8?
Case Report (n=1)
No
Does mexiletine or propranolol improve QTc interval in a patient with non-Timothy syndrome LQT8?
Answers are grounded in this paper and cite their sources.
Mexiletine and propranolol may be effective for managing QT prolongation in patients with non-Timothy syndrome LQT8 caused by CACNA1C variants.
No abstract yet. The journal hasn't published one we can show.
No takes yet. Share an insight, caveat, or question.
Aoki et al. (2020) conducted a case report in Long QT syndrome type 8 (LQT8) (n=1). Mexiletine vs. Baseline was evaluated on QTc interval. In an 18-year-old male with Long QT syndrome type 8, mexiletine infusion reduced the QTc(B) interval from 451 msec to 376 msec.
Synapse has enriched 10 related papers. Consider them for comparative context: