What does this research mean for the field?

Individual Salmonella Typhimurium bacteria exhibit a surprisingly broad spectrum of motion alignment angles, and while wild-type and FliC-expressing strains share similar motility, they differ significantly in their proportion of actively moving cells. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

Quantify the motion anisotropy, alignment, and motile activity of individual unconstrained Salmonella Typhimurium bacteria in bulk environments.

September 8, 2026ACS Nanoscience AuOpen Access

Motion Anisotropy of Individual, Unconfined Rod-Like-Shaped Salmonella Typhimurium Bacteria

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Authors

KDKevin Diestelhorst FGFereshteh Ghazisaeedi AKAnton Klimek

Discussion

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Overview

Single-particle tracking study reveals broad directional alignment angles in unconfined Salmonella Typhimurium, indicating distinct swimming activation profiles between flagellar variants.

Key Points

Quantify the motion anisotropy, alignment, and motile activity of individual unconstrained Salmonella Typhimurium bacteria in bulk environments.
Tracked the unconfined bulk movement of green-fluorescent protein (GFP)-labeled Salmonella Typhimurium using high-resolution fluorescence microscopy.
Decomposed individual bacterial trajectories into parallel and perpendicular components relative to the long body axis to quantify motile activity and alignment angles.
Evaluated motion parameters across wild-type bacteria and mutant strains with deletions in the flagellin genes fljB and fliC.
Salmonella Typhimurium exhibited a wide distribution of opening angles, spanning from complete alignment of the long axis with translational motion to no alignment.
Wild-type and FliC-expressing mutants displayed comparable motility characteristics, but differed significantly in the overall fraction of actively moving cells.

Cite This Study

Diestelhorst et al. (2026) studied this question.

synapsesocial.com/papers/6a9fd77658e84d0ff5b462c9 https://doi.org/10.1021/acsnanoscienceau.6c00080

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September 8, 2026ACS Nanoscience AuOpen Access

Motion Anisotropy of Individual, Unconfined Rod-Like-Shaped Salmonella Typhimurium Bacteria

View Full Paper

Ask AI

Bookmark

Authors

KDKevin Diestelhorst FGFereshteh Ghazisaeedi AKAnton Klimek

Discussion

Member takes

Overview

Single-particle tracking study reveals broad directional alignment angles in unconfined Salmonella Typhimurium, indicating distinct swimming activation profiles between flagellar variants.

Key Points

Quantify the motion anisotropy, alignment, and motile activity of individual unconstrained Salmonella Typhimurium bacteria in bulk environments.
Tracked the unconfined bulk movement of green-fluorescent protein (GFP)-labeled Salmonella Typhimurium using high-resolution fluorescence microscopy.
Decomposed individual bacterial trajectories into parallel and perpendicular components relative to the long body axis to quantify motile activity and alignment angles.
Evaluated motion parameters across wild-type bacteria and mutant strains with deletions in the flagellin genes fljB and fliC.
Salmonella Typhimurium exhibited a wide distribution of opening angles, spanning from complete alignment of the long axis with translational motion to no alignment.
Wild-type and FliC-expressing mutants displayed comparable motility characteristics, but differed significantly in the overall fraction of actively moving cells.

Cite This Study

Diestelhorst et al. (2026) studied this question.

synapsesocial.com/papers/6a9fd77658e84d0ff5b462c9 https://doi.org/10.1021/acsnanoscienceau.6c00080

View Full Paper

Ask AI

Bookmark