What does this research mean for the field?

Intestinal T-cell lymphoma can present atypically as intussusception or jejunal perforation, necessitating its consideration in the differential diagnosis of atypical bowel obstruction or perforation. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To describe atypical clinical presentations of intestinal T-cell lymphoma manifesting as acute jejunal perforation and ileocolic intussusception.

September 8, 2026Open Access

Intestinal T Cell Lymphoma Masquerading as Intussusception and Jejunal Perforation - Unusual Presentation of Two Cases

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Authors

MGMonika GathwalBhagat Phool Singh Mahila Vishwavidyalaya CGChiranjeev Gathwal RARuchi AgarwalBundelkhand University

Discussion

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Implication

Case series reports intestinal T-cell lymphoma presenting as jejunal perforation and intussusception in adult males, highlighting the need for early consideration during acute abdominal obstruction.

Key Points

To describe atypical clinical presentations of intestinal T-cell lymphoma manifesting as acute jejunal perforation and ileocolic intussusception.
Evaluated two clinical cases (a 79-year-old male and a 30-year-old male) presenting with acute abdominal symptoms (N=2).
Conducted diagnostic imaging (MRI and CT), emergency surgical exploration, gross tissue resection, histopathological evaluation, and immunohistochemical profiling.
In Case 1, a 79-year-old male had three jejunal perforations with atypical lymphoid cells showing CD3 and leukocyte common antigen (LCA) positivity consistent with enteropathy-associated T-cell lymphoma, resulting in death 7 days postoperatively.
In Case 2, a 30-year-old male presented with ileocolic intussusception and CD45-positive non-Hodgkin lymphoma lesions, achieving disease stability at 6 months of follow-up after surgical resection and chemotherapy.

Cite This Study

Gathwal et al. (2026) studied this question.

synapsesocial.com/papers/6a9fd7b758e84d0ff5b46afd https://doi.org/10.21276/apalm.3875

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Implication

Case series reports intestinal T-cell lymphoma presenting as jejunal perforation and intussusception in adult males, highlighting the need for early consideration during acute abdominal obstruction.

Intestinal T Cell Lymphoma Masquerading as Intussusception and Jejunal Perforation - Unusual Presentation of Two Cases

Discussion

Member takes

Implication

Key Points

Cite This Study

Intestinal T Cell Lymphoma Masquerading as Intussusception and Jejunal Perforation - Unusual Presentation of Two Cases

Discussion

Member takes

Implication

Key Points

Cite This Study

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