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September 8, 2026BiomedicinesOpen Access

Periodontal Disease and Incident Chronic Bronchitis: A Nationwide Population-Based Cohort Study

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Authors

SSSeon‐Ju SimBaekseok UniversityJMJa-Young MoonYonsei UniversityHSHye‐Sun ShinDongnam Health University

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Overview

Cohort study reveals an increased risk of chronic bronchitis among adults with periodontitis, indicating a possible role of oral inflammation in respiratory health.

Key Points

  • To evaluate the longitudinal association between claims-based periodontal disease status and incident chronic bronchitis in a nationwide population cohort.
  • Analyzed data from the Korean National Health Insurance Service–National Sample Cohort (2002–2015) comprising N=189,274 adults evaluated in 2002–2004 and followed from 2005 to 2015.
  • Categorized periodontal status as No PD, Gingivitis, or Periodontitis-related, and defined treatment by recorded scaling or root planing.
  • Estimated adjusted hazard ratios (aHRs) and 95% confidence intervals (CIs) for incident chronic bronchitis using Cox proportional hazards regression models.
  • Incident chronic bronchitis occurred in 52,955 participants (28.0%) over the follow-up period.
  • Periodontitis-related diagnoses were associated with a higher risk of chronic bronchitis compared to no periodontal disease (aHR = 1.05, 95% CI = 1.02–1.08), whereas gingivitis showed no association (aHR = 1.01, 95% CI = 0.99–1.03).
  • Risk was elevated among participants without recorded periodontal treatment (aHR = 1.08, 95% CI = 1.03–1.12) and those aged 40–59 years (aHR = 1.06, 95% CI = 1.02–1.11), but was not significant among treated individuals (aHR = 0.86, 95% CI = 0.74–1.01).

Cite This Study

Sim et al. (2026) studied this question.

synapsesocial.com/papers/6a9fd80458e84d0ff5b472d9https://doi.org/10.3390/biomedicines14091999
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