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September 8, 2026DiabetologyOpen Access

Understanding Psychological Functioning in Type 1 Diabetes: Toward an Integrated Framework

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Authors

EMEmanuele Maria Merlo

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Overview

Conceptual review reveals dynamic interactions between mental and metabolic processes in type 1 diabetes, highlighting the need for an integrated framework to personalize long-term care.

Key Points

  • Address conceptual fragmentation in diabetes psychology by proposing an integrated psychobiological framework that connects psychological, behavioral, and metabolic dimensions across the disease trajectory.
  • Analyzed conceptual gaps in existing literature where psychological constructs in type 1 diabetes mellitus are studied in isolation from behavioral and biological factors.
  • Modeled individual traits, environmental contexts, psychological mechanisms, and metabolic markers as components of an interconnected, dynamic system.
  • Delineated reciprocal, mediated, and moderated pathways connecting emotional functioning, daily self-care, and metabolic outcomes.
  • Demonstrated how psychobiological interactions evolve across developmental life stages and disease durations to drive clinical variance.
  • Outlined structured operational pathways to guide future empirical research and facilitate tailored clinical assessment and intervention.

Cite This Study

Emanuele Maria Merlo (2026) studied this question.

synapsesocial.com/papers/6a9fd83b58e84d0ff5b47a19https://doi.org/10.3390/diabetology7090175
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