Key result
Serum omentin-1 concentrations were significantly reduced in 220 patients with atrial fibrillation compared to 115 healthy controls, and negatively correlated with left atrial diameter.
Why the study?
Are serum omentin-1 concentrations associated with the presence and type of atrial fibrillation?
Cross-Sectional (n=335)
Are serum omentin-1 concentrations associated with the presence and type of atrial fibrillation?
Lower serum omentin-1 concentrations are associated with the presence and progression of atrial fibrillation as well as left atrial remodeling.
Omentin-1 reduction was associated with AF and LA remodeling; cross-sectional data leave causal and prognostic roles open.
BACKGROUND Omentin-1 is one of the adipokines associated with obesity, diabetes, and coronary heart disease development. We determined to investigate whether serum omentin-1 concentrations were correlated with the presence of atrial fibrillation (AF). MATERIAL AND METHODS Serum omentin-1 concentrations were examined in a cross-sectional population that included 220 patients with AF (70 with paroxysmal AF, 78 with persistent AF, and 72 with permanent AF) and 115 healthy controls. RESULTS Reduced serum omentin-1 concentrations were found in AF patients compared to the controls. In addition, patients with permanent AF had lower serum omentin-1 concentrations compared to patients with persistent AF and patients with paroxysmal AF. Significantly decreased serum omentin-1 concentrations were observed in persistent AF patients compared to paroxysmal AF patients. Spearman correlation analysis suggested that serum omentin-1 concentrations were negatively correlated with left atrial diameter in AF patients. CONCLUSIONS Serum omentin-1 concentrations were correlated with the presence of AF and atrial remolding.
No takes yet. Share an insight, caveat, or question.
Tao et al. (2016) conducted a cross-sectional in Atrial Fibrillation (n=335). Serum omentin-1 concentrations vs. Healthy controls was evaluated on Presence of atrial fibrillation. Serum omentin-1 concentrations were significantly reduced in 220 patients with atrial fibrillation compared to 115 healthy controls, and negatively correlated with left atrial diameter.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: