Why the study?
Does a hypocaloric diet-induced weight loss increase circulating omentin-1 concentrations in obese subjects?
Population
35 Caucasian obese volunteers, non-smokers, not receiving statins or antidiabetic medication, recruited at…
Design
Cohort
Follow-up
4 months
Key result
A 4-month hypocaloric diet significantly increased circulating omentin-1 concentrations from 44.9 to 53.4 ng/ml (p < 0.001) in obese subjects, correlating with improved insulin sensitivity.
Authors
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Omentin-1 rise after diet-induced weight loss should not yet change practice; leaves open causal role in insulin sensitivity.
Cohort (n=35)
No
Does a hypocaloric diet-induced weight loss increase circulating omentin-1 concentrations in obese subjects?
Absolute Event Rate: 53.41% vs 44.9%
p-value: p=<0.001
Weight loss induced by a hypocaloric diet significantly increases circulating omentin-1 concentrations, which correlates with improved insulin sensitivity.
Moreno‐Navarrete et al. (2010) conducted a cohort in Obesity (n=35). Hypocaloric diet vs. Baseline was evaluated on Circulating omentin-1 concentration (p=<0.001). A 4-month hypocaloric diet significantly increased circulating omentin-1 concentrations from 44.9 to 53.4 ng/ml (p < 0.001) in obese subjects, correlating with improved insulin sensitivity.