Key result
A 1-year weight reduction program significantly increased omentin-1 plasma levels from a median of 5.31 ng/ml to 9.74 ng/ml in obese patients with type 1 diabetes.
Why the study?
Does a weight reduction program improve omentin-1 plasma levels and cholesterol metabolism in obese patients with type 1 diabetes mellitus?
Population
14 obese patients with type 1 diabetes mellitus (BMI >30 kg/m², age 29-62 years)
Comparison
Weight reduction program consisting of 1 week of… vs Baseline (pre-intervention)
Design
Cohort
Follow-up
1 year
Authors
Loading...
Supports weight reduction evaluation in obese T1D; hypothesis-generating for omentin-1 links to cholesterol metabolism.
Observational (n=14)
No
Does a weight reduction program improve omentin-1 plasma levels and cholesterol metabolism in obese patients with type 1 diabetes mellitus?
Absolute Event Rate: 9.74% vs 5.31%
p-value: p=<0.001
Weight reduction in obese patients with type 1 diabetes significantly increases omentin-1 levels, which correlates with improvements in cholesterol metabolism.
Lesná et al. (2015) conducted an observational in Obese patients with diabetes mellitus type 1 (n=14). Weight reduction program vs. Baseline (pre-intervention) was evaluated on Omentin-1 plasma levels at 1 year (p=<0.001). A 1-year weight reduction program significantly increased omentin-1 plasma levels from a median of 5.31 ng/ml to 9.74 ng/ml in obese patients with type 1 diabetes.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: