Multilocular Encephalomalacia

The genesis of cavitation in the central nervous system presents an important problem.This holds true for porencephalia, syringomyelia, cystic tumours, Wilson's disease, and for cases of multilocular encephalomalacia.The last condition has been described under many different names which are summarized in Table I.I have accepted the name multilocular encephalomalacia as it combines in two words the main characteristics, namely the multiple cavity formation and the softening.Some in- vestigators have concerned themselves solely with the anatomy and physiology of this condition (Edinger and Fischer, 1913;Jakob, 1931;Verhaart, 1936), but most papers have dealt with the patho- genesis.