Key result
Cerebral autoregulation in patients with recurrent neurally mediated syncope did not differ from that of normal control subjects during rest or head-up tilt.
Why the study?
Is cerebral autoregulation impaired in patients with recurrent neurally mediated syncope compared to normal controls during head-up tilt?
Population
37 patients with recurrent neurally mediated syncope (NMS) and 15 normal control subjects (total n=52).
Comparison
80 degrees head-up tilt testing with continuous… vs Normal control subjects undergoing the same…
Design
Case-control
Authors
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Intact autoregulation does not implicate cerebral blood flow impairment in recurrent neurally mediated syncope; leaves open alternative mechanisms for study.
Case-Control (n=52)
Is cerebral autoregulation impaired in patients with recurrent neurally mediated syncope compared to normal controls during head-up tilt?
Cerebral autoregulation remains intact in patients with neurally mediated syncope, suggesting that the condition is not driven by an intrinsic impairment in cerebral blood flow regulation.
Schondorf et al. (2001) conducted a case-control in Neurally mediated syncope (n=52). Neurally mediated syncope vs. Normal subjects was evaluated on Cerebral autoregulation (static and dynamic). Cerebral autoregulation in patients with recurrent neurally mediated syncope did not differ from that of normal control subjects during rest or head-up tilt.
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