Epidemiological, clinical, aetiological and therapeutic aspects of polymorphous light eruption, a very common disease in Mexico, are reviewed. Twenty-five patients with this disease were treated with thalidomide over a period of 45 to 150 days with a dose depending on age: 100 to 200 mg a day. The results were satisfactory in 88% of the cases without any important side-effect. The teratogenic action of the drug is stressed and the authors think that although the action mechanism of the drug remains unknown, it may shed new light on the understanding and treatment of this disease.
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Saúl et al. (1976) studied this question.