Key result
Obesity was associated with significantly reduced global and local resting-state brain network efficiency and decreased modularity compared with healthy controls.
Population
80 participants, recruited in Cambridge, UK. Obese subjects had BMI >30 kg/m2; healthy controls had BMI…
Design
Cross-sectional
Authors
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Obesity-related brain network changes may signal cognitive vulnerability; hypothesis-generating and requires longitudinal studies before clinical relevance.
Cross-Sectional (n=80)
No
p-value: p=0.0012
Obesity is associated with disrupted global brain network properties and motor cortico-striatal networks, suggesting a neurobiological basis for pathological food misuse.
Baek et al. (2016) conducted a cross-sectional in Obesity and Binge Eating Disorder (n=80). Obesity vs. Healthy controls was evaluated on Global network efficiency (p=0.0012). Obesity was associated with significantly reduced global and local resting-state brain network efficiency and decreased modularity compared with healthy controls.
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