What question did this study set out to answer?

To determine whether cardiac-induced brain-stem pulsatility hinders subcortical fMRI and evaluate whether cardiac gating permits reliable imaging of human subcortical auditory structures.

January 1, 1998Human Brain Mapping

Imaging subcortical auditory activity in humans

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To determine whether cardiac-induced brain-stem pulsatility hinders subcortical fMRI and evaluate whether cardiac gating permits reliable imaging of human subcortical auditory structures.
Implemented functional magnetic resonance imaging (fMRI) coupled with cardiac gating to synchronize image collection with the cardiac cycle.
Mapped sound-evoked responses in the auditory cortices and subcortical inferior colliculi in awake human listeners.
Auditory activation in both the inferior colliculi and auditory cortex became significantly more discernible with the application of cardiac gating.
Signal improvement in the inferior colliculi stemmed specifically from reduced signal variability rather than greater percent signal change, identifying pulsatile motion as the primary imaging confound.

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Implication

Imaging experiment demonstrates that cardiac gating improves subcortical auditory fMRI detection in humans, indicating that motion reduction enables functional brain-stem mapping.

Cite This Study

Guimarães et al. (1998) studied this question.

synapsesocial.com/papers/6a9fe4b460d48b61846188ad https://doi.org/10.1002/(sici)1097-0193(1998)6:1<33::aid-hbm3>3.0.co;2-m

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Implication

Imaging experiment demonstrates that cardiac gating improves subcortical auditory fMRI detection in humans, indicating that motion reduction enables functional brain-stem mapping.

Imaging subcortical auditory activity in humans

Key Points

Discussion

Implication

Cite This Study

Imaging subcortical auditory activity in humans

Key Points

Discussion

Implication

Cite This Study

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