Key result
Comorbid anxiety and/or depression in patients hospitalized for acute exacerbation of COPD was associated with lower in-hospital mortality (OR 0.74) but higher risks of readmission within 1 year.
Why the study?
To investigate the temporal trend in anxiety and/or depression prevalence in patients hospitalized for AECOPD in Beijing and their association with adverse outcomes.
Does comorbid anxiety and/or depression affect adverse outcomes in patients hospitalized for AECOPD?
Cohort (n=382,125)
Yes
Does comorbid anxiety and/or depression affect adverse outcomes in patients hospitalized for AECOPD?
Odds Ratio: 0.74 (95% CI 0.63–0.88)
Absolute Event Rate: 2.1% vs 3%
p-value: p=<0.001
Comorbid anxiety and/or depression in AECOPD patients is associated with lower in-hospital mortality but longer hospital stays, higher costs, and increased 1-year readmission risk.
No takes yet. Share an insight, caveat, or question.
Stabilized ~3% prevalence signals persistent readmission and cost burden in AECOPD; observational data leave causal effects and practice changes open.
Lin et al. (2022) conducted a cohort in Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) (n=382,125). Anxiety and/or depression vs. No anxiety and/or depression was evaluated on In-hospital mortality (OR 0.74, 95% CI 0.63-0.88, p=<0.001). Comorbid anxiety and/or depression in patients hospitalized for acute exacerbation of COPD was associated with lower in-hospital mortality (OR 0.74) but higher risks of readmission within 1 year.
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