Key result
The subendothelium of human brain arteries showed a highly variable, helical arrangement of tissue, contrasting with the highly coherent, circumferentially oriented medial fabric.
Observational (n=16)
The subendothelium of human brain arteries exhibits a highly variable, helical organization of smooth muscle and collagen compared to the highly coherent, circumferential organization of the media.
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Heterogeneous subendothelial architecture in cerebral arteries may alter local biomechanics; leaves open its role in cerebrovascular disease.
Finlay et al. (1991) conducted an observational in Atherosclerosis (n=16). Subendothelium structural organization vs. Medial fabric was evaluated on Directional organization of smooth muscle cells and collagen. The subendothelium of human brain arteries showed a highly variable, helical arrangement of tissue, contrasting with the highly coherent, circumferentially oriented medial fabric.
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