Yet Another Variant Of Gbs With Hyperrelexia And Loss Of Pain

Guillain Barre Syndrome is an acute demyelinating disorder of spinal roots and peripheralnerves occasionally the cranial nerves due to an immune-mediated disturbance involving the peripheral myelin sheath. It is characterized clinically by acute ascending type of motor weakness of limbs with hypoor a reflexia with preserved sensation and autonomic nervous system. However, other GBS variants like pure acute panautonomia3, Miller Fisher syndrome4, polyneuritis cranialis, pharyngeal-cervical-brachial variant5, facial diplegia with hyper reflexes6 have also been reported. Patient presented with sub acute , progressive, weakness of all four limbsassociated with hyper reflexia and loss of pain and temperature, with electrophysiological features suggestive of severe demyelinating neuropathy motor as well as sensory component and responding to IVIG.