Key result
High preoperative frailty was associated with increased odds of non-home discharge (OR 2.1; 95% CI 1.03-2.99), and moderate frailty with higher hospital readmission (OR 1.5; 95% CI 1.01-1.82).
Why the study?
The study aimed to evaluate preoperative frailty using the laboratory-based frailty index (FI-LAB) and its association with clinical outcomes in older adults undergoing brain tumor surgery.
Does preoperative frailty assessed by FI-LAB predict hospital readmission and non-home discharge in older adults undergoing brain tumor surgery?
Cohort (n=111)
No
Does preoperative frailty assessed by FI-LAB predict hospital readmission and non-home discharge in older adults undergoing brain tumor surgery?
Odds Ratio: 2.1 (95% CI 1.03–2.99)
Preoperative frailty assessed by FI-LAB is significantly associated with increased risks of hospital readmission and non-home discharge in older adults undergoing brain tumor surgery.
FI-LAB frailty was associated with readmission and non-home discharge after brain tumor surgery; leaves open prospective validation before clinical adoption.
This retrospective cohort study aimed to evaluate preoperative frailty in older adults undergoing brain tumor surgery using the laboratory-based frailty index (FI-LAB) and its association with clinical outcomes. Data were from electronic medical records of individuals aged ≥ 65 years who had brain tumor surgery between 2015 and 2022 at a general hospital in Seoul, South Korea. The FI-LAB included 26 preoperative laboratory tests and five vitality parameters. Of the 111 patients (mean age 75.4 years; 55% women; 63.1% had benign tumors), 35.1% exhibited moderate or high frailty. Moderate frailty was associated with higher hospital readmission rates (OR = 1.5; 95% CI, 1.01-1.82), and high frailty was linked to non-home discharge (OR = 2.1; 95% CI, 1.03-2.99). Assessing preoperative frailty with the FI-LAB may help identify risks of readmission or non-home discharge. Future studies with larger samples are needed to validate these findings. Nurses should integrate frailty assessment into practice to improve postoperative outcomes.
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Kim et al. (2025) conducted a cohort in Brain tumor (n=111). Preoperative frailty assessed by FI-LAB vs. Lower frailty levels was evaluated on Non-home discharge (for high frailty) (OR 2.1, 95% CI 1.03-2.99). High preoperative frailty was associated with increased odds of non-home discharge (OR 2.1; 95% CI 1.03-2.99), and moderate frailty with higher hospital readmission (OR 1.5; 95% CI 1.01-1.82).
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