Routine home treatment of deep vein thrombosis
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Key result
Home treatment of deep vein thrombosis was feasible in 78.6% of outpatients, with no episodes of clinical pulmonary embolism or major bleeding observed during three months of follow-up.
Why the study?
Does home treatment with low molecular weight heparin maintain safety and efficacy compared to hospital admission in patients with acute deep vein thrombosis?
Population
Patients with acute deep vein thrombosis (DVT)
Comparison
Home treatment with subcutaneous low molecular… vs Hospital admission with intravenous…
Design
Editorial
Authors
Discussion
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Implication
Routine home treatment of acute deep vein thrombosis with low molecular weight heparin is a safe and feasible alternative to hospital admission for the majority of patients, provided adequate multidisciplinary support is available.
Structured PICO
Does home treatment with low molecular weight heparin maintain safety and efficacy compared to hospital admission in patients with acute deep vein thrombosis?
P
Population
117 consecutive outpatients with confirmed proximal or distal deep vein thrombosis evaluated for the feasibility and safety of home treatment over 3 months.
I
Intervention
Home treatment with subcutaneous low molecular weight heparin
C
Comparator
Hospital admission with intravenous unfractionated heparin
O
Outcome
Safety and feasibility (recurrent venous thromboembolism, major bleeding, and death)safety
Routine home treatment of acute deep vein thrombosis with low molecular weight heparin is a safe and feasible alternative to hospital admission for the majority of patients, provided adequate multidisciplinary support is available.
Limitations
- Up to 20% of patients are unsuitable for home treatment due to high thrombotic load, bleeding risk, or logistic reasons.
- Requires adequate resources to establish a multidisciplinary clinical service.
- Safety and effectiveness of home treatment programmes in individual centres need to be monitored.
- Up to 20% of patients remain unsuitable for home treatment due to high thrombotic load, bleeding risk, or other medical/logistic reasons
- Successful home treatment requires adequate resources to establish a multidisciplinary clinical service
- Safety and effectiveness of home treatment programmes in individual centres need to be monitored
Cite This Study
John W. Eikelboom (2001) conducted an editorial in Deep vein thrombosis (n=117). Home treatment with low molecular weight heparin vs. Hospital admission was evaluated on Episodes of clinical pulmonary embolism or major bleeding. Home treatment of deep vein thrombosis was feasible in 78.6% of outpatients, with no episodes of clinical pulmonary embolism or major bleeding observed during three months of follow-up.
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