Key result
Decreased small arterial elasticity independently predicted an increased risk of cardiovascular events and cardiovascular death in Chinese patients with angiographic CAD (P < .001).
Why the study?
Does decreased small arterial elasticity predict future cardiovascular events in Chinese patients with angiographic CAD?
Cohort (n=365)
Does decreased small arterial elasticity predict future cardiovascular events in Chinese patients with angiographic CAD?
Decreased small arterial elasticity serves as an independent predictor of future cardiovascular events in patients with established angiographic coronary artery disease.
May inform risk stratification in angiographic CAD; hypothesis-generating pending prospective trials.
Arterial elasticity has been shown to predict cardiovascular disease (CVD) in apparently healthy populations. The present study aimed to explore whether arterial elasticity could predict CVD events in Chinese patients with angiographic coronary artery disease (CAD). Arterial elasticity of 365 patients with angiographic CAD was measured. During follow-up (48 months; range 6-65), 140 CVD events occurred (including 34 deaths). Univariate Cox analysis demonstrated that both large arterial elasticity and small arterial elasticity were significant predictors of CVD events. Multivariate Cox analysis indicated that small arterial elasticity remained significant. Kaplan-Meier analysis showed that the probability of having a CVD event/CVD death increased with a decrease of small arterial elasticity (P < .001, respectively). Decreased small arterial elasticity independently predicts the risk of CVD events in Chinese patients with angiographic CAD.
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Wan et al. (2013) conducted a cohort in Angiographic coronary artery disease (n=365). Decreased small arterial elasticity was evaluated on Cardiovascular disease events (p=<.001). Decreased small arterial elasticity independently predicted an increased risk of cardiovascular events and cardiovascular death in Chinese patients with angiographic CAD (P < .001).
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