Key result
A 12-week dietary modification program significantly reduced serum ANGPTL2 levels and arterial stiffness in overweight and obese men, with the reduction in ANGPTL2 correlating with improved arterial compliance.
Why the study?
Weight loss reduces obesity-induced arterial stiffening, but the effects of dietary modification on circulating pro-inflammatory ANGPTL2 levels and arterial stiffness in overweight and obese men were unknown.
Does a 12-week dietary modification program improve arterial stiffness and reduce serum ANGPTL2 levels in overweight and obese men?
Does a 12-week dietary modification program improve arterial stiffness and reduce serum ANGPTL2 levels in overweight and obese men?
Dietary modification in overweight and obese men reduces circulating ANGPTL2 levels, which correlates with a reduction in arterial stiffness.
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Dietary modification may reduce ANGPTL2 and arterial stiffness in obese men; leaves open causal mediation in controlled trials.
Park et al. (2019) studied Overweight and obesity (n=22). Dietary modification vs. Baseline was evaluated on Serum ANGPTL2 levels and arterial stiffness (arterial compliance and β-stiffness index). A 12-week dietary modification program significantly reduced serum ANGPTL2 levels and arterial stiffness in overweight and obese men, with the reduction in ANGPTL2 correlating with improved arterial compliance.
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