Key result
Enteral pseudoephedrine enables weaning from IV vasoactive support in central sympathetic insufficiency.
Why the study?
The authors describe a patient with posterior hypothalamus lesions associated with reduced sympathetic drive and their management with a readily available sympathomimetic drug.
Does enteral pseudoephedrine improve hemodynamics and allow weaning of intravenous vasoactive support in a patient with central sympathetic insufficiency?
Case Report (n=1)
No
Does enteral pseudoephedrine improve hemodynamics and allow weaning of intravenous vasoactive support in a patient with central sympathetic insufficiency?
Enteral pseudoephedrine may serve as an effective temporary pharmacological intervention for central sympathetic insufficiency to facilitate weaning from intravenous vasoactive medications.
May allow weaning of IV vasoactives in central sympathetic insufficiency; hypothesis-generating and requires prospective validation.
No abstract yet. The journal hasn't published one we can show.
No takes yet. Share an insight, caveat, or question.
Wcislo et al. (2026) conducted a case report in Central sympathetic insufficiency (n=1). Pseudoephedrine was evaluated on Weaning off intravenous vasoactive support. Enteral pseudoephedrine successfully allowed a patient with central sympathetic insufficiency to wean off intravenous vasoactive support and transfer for chemotherapy.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: