What question did this study set out to answer?

To characterize and compare the anatomical distribution and morphology of neuropeptide Y-immunoreactive cell bodies and nerve terminals across hippocampal and retrohippocampal regions in rats and monkeys.

February 15, 1986The Journal of Comparative Neurology

Neuropeptide Y innervation of the hippocampal region in the rat and monkey brain

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Authors

CKChrister KöhlerUniversity of Mary LELars ErikssonKarlstad University SDStephen DaviesUniversity of Auckland

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Implication

Comparative neuroanatomical study reveals conserved yet distinct neuropeptide Y distribution in rat and monkey hippocampus, indicating preserved neuromodulatory roles across species.

Key Points

To characterize and compare the anatomical distribution and morphology of neuropeptide Y-immunoreactive cell bodies and nerve terminals across hippocampal and retrohippocampal regions in rats and monkeys.
Immunohistochemical labeling using anti-neuropeptide Y antibodies in colchicine-pretreated rats and untreated cynomolgus monkeys.
Anatomical and morphological analysis across Ammon's horn, dentate gyrus, subicular complex, and entorhinal cortex.
Neuropeptide Y-immunoreactive somas concentrated heavily in the dentate hilus, subgranular zone, and stratum oriens of Ammon's horn in both species, with varying cell morphologies (polymorphic, spheroid, and pyramidal basket cells).
Dense fiber networks innervate the entire hippocampal region in both species, with monkey brains exhibiting markedly denser innervation within the dentate molecular layer compared to rats.
Retrohippocampal areas, particularly the entorhinal cortex, display widespread fiber plexuses across all layers, with soma localization preferentially in deeper cortical layers (V–VI).

Cite This Study

Köhler et al. (1986) studied this question.

synapsesocial.com/papers/6aa0009fa44af08ec7babd8d https://doi.org/10.1002/cne.902440310

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Implication

Comparative neuroanatomical study reveals conserved yet distinct neuropeptide Y distribution in rat and monkey hippocampus, indicating preserved neuromodulatory roles across species.

Neuropeptide Y innervation of the hippocampal region in the rat and monkey brain

Discussion

Member takes

Implication

Key Points

Cite This Study

Neuropeptide Y innervation of the hippocampal region in the rat and monkey brain

Discussion

Member takes

Implication

Key Points

Cite This Study

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Also Consider