Key result
Bifocal right ventricular pacing significantly improved left ventricular ejection fraction from 26% to 36% (P<0.0008), as well as NYHA class, 6-minute walk test, and quality-of-life scores.
Why the study?
Does bifocal right ventricular pacing improve LV EF, exercise capacity, and quality of life in patients with chronic heart failure eligible for CRT?
RCT (n=42)
Single-blind
Crossover
Does bifocal right ventricular pacing improve LV EF, exercise capacity, and quality of life in patients with chronic heart failure eligible for CRT?
p-value: p=<0.0008
Bifocal right ventricular pacing significantly improves ejection fraction, functional class, exercise capacity, and quality of life in patients with chronic drug-refractory heart failure eligible for CRT.
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Supports bifocal RV pacing in CRT candidates; extends randomized evidence for alternative RV configurations in heart failure.
J. et al. (2007) conducted an RCT in Heart failure (n=42). Bifocal right ventricular pacing vs. Control pacing mode was evaluated on Improvement in left ventricular ejection fraction, 6 min walk test, Minnesota quality-of-life score, and NYHA classification (p=<0.0008). Bifocal right ventricular pacing significantly improved left ventricular ejection fraction from 26% to 36% (P<0.0008), as well as NYHA class, 6-minute walk test, and quality-of-life scores.
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