Key result
Rare alleles of apo B signal peptide and HindIII/LPL polymorphisms were significantly less frequent in coronary artery disease patients compared to healthy controls (p < 0.05).
Why the study?
Are specific genetic polymorphisms associated with coronary artery disease and lipid level variability?
Case-Control
Are specific genetic polymorphisms associated with coronary artery disease and lipid level variability?
p-value: p=< 0.05
Specific genetic polymorphisms in apo B, apo E, and LPL are associated with coronary artery disease prevalence and lipid profile variations.
No takes yet. Share an insight, caveat, or question.
Should not guide clinical genetic testing for CAD; leaves open causal role pending larger prospective studies.
Régis‐Bailly et al. (1996) conducted a case-control in Coronary artery disease. Apo B, apo E, and LPL genetic polymorphisms vs. Healthy controls / alternative alleles was evaluated on Allele partition between cases and controls (p=< 0.05). Rare alleles of apo B signal peptide and HindIII/LPL polymorphisms were significantly less frequent in coronary artery disease patients compared to healthy controls (p < 0.05).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: