What question did this study set out to answer?

To assess the validity and utility of total cholesterol screening in school-age children for predicting adult hypercholesterolemia requiring continuing surveillance and intervention.

December 19, 1990JAMA

Use of cholesterol measurements in childhood for the prediction of adult hypercholesterolemia. The Muscatine Study

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Authors

RLRonald M. LauerBoston University

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Implication

Cohort study reveals poor adult hypercholesterolemia prediction in children, suggesting caution regarding universal screening.

Key Points

To assess the validity and utility of total cholesterol screening in school-age children for predicting adult hypercholesterolemia requiring continuing surveillance and intervention.
Prospective longitudinal cohort study following N=2,367 participants examined repeatedly between ages 8 and 18 years and reevaluated at ages 20 to 30 years.
Tracked childhood cholesterol concentrations exceeding the 75th and 90th percentiles on two occasions to evaluate qualification for adult intervention under National Cholesterol Education Program criteria.
Among children with cholesterol levels exceeding the 75th percentile on two occasions, 75% of girls and 56% of boys did not meet National Cholesterol Education Program criteria for adult intervention.
Among children exceeding the 90th percentile on two occasions, 57% of girls and 30% of boys failed to meet criteria requiring intervention as adults.

Cite This Study

Ronald M. Lauer (1990) studied this question.

synapsesocial.com/papers/6aa00918516c2ec66e7c7365 https://doi.org/10.1001/jama.264.23.3034

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Use of cholesterol measurements in childhood for the prediction of adult hypercholesterolemia. The Muscatine Study

Discussion

Member takes

Implication

Key Points

Cite This Study

Use of cholesterol measurements in childhood for the prediction of adult hypercholesterolemia. The Muscatine Study

Discussion

Member takes

Implication

Key Points

Cite This Study

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