What does this research mean for the field?

Photocatalysis provides a sustainable, efficient, and versatile alternative to conventional transition-metal catalysis for carbon-carbon bond formation, enabling the selective activation of traditionally unreactive substrates through radical-mediated pathways. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To comprehensively review advances in visible-light-mediated carbon–carbon bond coupling reactions reported from 2023 to early 2026, evaluating mechanistic paradigms and synthetic utility.

September 8, 2026OrganicsOpen Access

Photocatalytic C–C Bond Coupling Reactions Towards Organic Transformation—Recent Updates

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Authors

PSPriyanka R. Sakhare AJAmit K. Jha PKPraveen Kumar

Discussion

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Overview

Narrative review demonstrates major advances in visible-light photocatalytic carbon-carbon bond coupling reactions, highlighting sustainable pathways for complex molecule synthesis.

Key Points

To comprehensively review advances in visible-light-mediated carbon–carbon bond coupling reactions reported from 2023 to early 2026, evaluating mechanistic paradigms and synthetic utility.
Synthesized research literature from 2023 through early 2026 covering C(sp3)–C(sp3), C(sp3)–C(sp2), and C(sp2)–C(sp2) bond formation.
Assessed catalytic frameworks including dual photoredox/transition-metal systems, metal-free catalysts, hydrogen atom transfer, proton-coupled electron transfer, and enantioselective pathways.
Visible-light photocatalysis facilitates the mild activation of traditionally inert substrates such as alkanes, alcohols, haloarenes, and carboxylic acids via radical-mediated pathways.
Decarboxylative, deaminative, and radical–radical coupling strategies provide robust functional-group tolerance and high atom economy without demanding extreme reaction conditions.

Cite This Study

Sakhare et al. (2026) studied this question.

synapsesocial.com/papers/6aa0091858e84d0ff5b47bfa https://doi.org/10.3390/org7030036

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September 8, 2026OrganicsOpen Access

Photocatalytic C–C Bond Coupling Reactions Towards Organic Transformation—Recent Updates

View Full Paper

Ask AI

Bookmark

Authors

PSPriyanka R. Sakhare AJAmit K. Jha PKPraveen Kumar

Discussion

Member takes

Overview

Narrative review demonstrates major advances in visible-light photocatalytic carbon-carbon bond coupling reactions, highlighting sustainable pathways for complex molecule synthesis.

Key Points

To comprehensively review advances in visible-light-mediated carbon–carbon bond coupling reactions reported from 2023 to early 2026, evaluating mechanistic paradigms and synthetic utility.
Synthesized research literature from 2023 through early 2026 covering C(sp3)–C(sp3), C(sp3)–C(sp2), and C(sp2)–C(sp2) bond formation.
Assessed catalytic frameworks including dual photoredox/transition-metal systems, metal-free catalysts, hydrogen atom transfer, proton-coupled electron transfer, and enantioselective pathways.
Visible-light photocatalysis facilitates the mild activation of traditionally inert substrates such as alkanes, alcohols, haloarenes, and carboxylic acids via radical-mediated pathways.
Decarboxylative, deaminative, and radical–radical coupling strategies provide robust functional-group tolerance and high atom economy without demanding extreme reaction conditions.

Cite This Study

Sakhare et al. (2026) studied this question.

synapsesocial.com/papers/6aa0091858e84d0ff5b47bfa https://doi.org/10.3390/org7030036

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