Difference in Susceptibility of Mice Raised under Barrier‐Sustained (SPF) or Conventional Conditions to Infectious Megaenteron

In has been suggested that susceptibility to infection with murine enteropathogenic Escherichia coli (E. coli 0115a, c: K(B)), a causative agent of megaenteron of mice, is influenced by age, strain and intestinal flora of the mice (3, 5).The present investigation was conducted to determine the susceptibility of several strains of mice raised under different environmental conditions.For mice from barrier sustained (SPE) colonies, strain CF # 1, and strain DDD